Clinical characteristics and predictors of mortality in young adults with severe COVID-19: a retrospective observational study

Abstract Background and objective Little is yet known whether pathogenesis of COVID-19 different between young elder patients. Our study aimed to investigate the clinical characteristics provide predictors mortality for adults with severe COVID-19. Methods A total 77 confirmed were recruited retrospectively at Tongji Hospital. Clinical characteristics, laboratory findings, treatment outcomes obtained from electronic medical records. The prognostic effects variables analyzed using logistic regression model. Results In this retrospective cohort, non-survivors showed higher incidence dyspnea co-existing abnormalities, compared survivals in Multivariate analysis that lymphopenia, elevated level d-dimer, hypersensitive cardiac troponin I (hs-CTnI) high sensitivity C-reactive protein (hs-CRP) independent Further severely two or more factors abnormalities above would be prone death. similar predictive effect four had been observed all-age patients Conclusion Lymphopenia, hs-CTnI hs-CRP predicted